Cargando…
Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liver
BACKGROUND: Mice with humanized livers are important models to study drug toxicology testing, development of hepatitis virus treatments, and hepatocyte transplantation therapy. However, the huge difference between mouse and human in size and anatomy limited the application of humanized mice in inves...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900390/ https://www.ncbi.nlm.nih.gov/pubmed/35255981 http://dx.doi.org/10.1186/s13578-022-00760-3 |