Functions and consequences of AID/APOBEC-mediated DNA and RNA deamination

The AID/APOBEC polynucleotide cytidine deaminases have historically been classified as either DNA mutators or RNA editors based on their first identified nucleic acid substrate preference. DNA mutators can generate functional diversity at antibody genes but also cause genomic instability in cancer....

Descripción completa

Detalles Bibliográficos
Autores principales: Pecori, Riccardo, Di Giorgio, Salvatore, Paulo Lorenzo, J., Nina Papavasiliou, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900473/
https://www.ncbi.nlm.nih.gov/pubmed/35256818
http://dx.doi.org/10.1038/s41576-022-00459-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900473/
https://www.ncbi.nlm.nih.gov/pubmed/35256818
http://dx.doi.org/10.1038/s41576-022-00459-8

Ejemplares similares