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Protein C or Protein S deficiency associates with paradoxically impaired platelet‐dependent thrombus and fibrin formation under flow

BACKGROUND: Low plasma levels of protein C or protein S are associated with venous thromboembolism rather than myocardial infarction. The high coagulant activity in patients with thrombophilia with a (familial) defect in protein C or S is explained by defective protein C activation, involving thromb...

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Detalles Bibliográficos
Autores principales: Brouns, Sanne L. N., Tullemans, Bibian M. E., Bulato, Cristiana, Perrella, Gina, Campello, Elena, Spiezia, Luca, van Geffen, Johanna P., Kuijpers, Marijke J. E., van Oerle, René, Spronk, Henri M. H., van der Meijden, Paola E. J., Simioni, Paolo, Heemskerk, Johan W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900581/
https://www.ncbi.nlm.nih.gov/pubmed/35284776
http://dx.doi.org/10.1002/rth2.12678