Cargando…

Protein C or Protein S deficiency associates with paradoxically impaired platelet‐dependent thrombus and fibrin formation under flow

BACKGROUND: Low plasma levels of protein C or protein S are associated with venous thromboembolism rather than myocardial infarction. The high coagulant activity in patients with thrombophilia with a (familial) defect in protein C or S is explained by defective protein C activation, involving thromb...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brouns, Sanne L. N., Tullemans, Bibian M. E., Bulato, Cristiana, Perrella, Gina, Campello, Elena, Spiezia, Luca, van Geffen, Johanna P., Kuijpers, Marijke J. E., van Oerle, René, Spronk, Henri M. H., van der Meijden, Paola E. J., Simioni, Paolo, Heemskerk, Johan W. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900581/ https://www.ncbi.nlm.nih.gov/pubmed/35284776 http://dx.doi.org/10.1002/rth2.12678

Ejemplares similares

Platelet-primed interactions of coagulation and anticoagulation pathways in flow-dependent thrombus formation
por: Brouns, Sanne L. N., et al.
Publicado: (2020)

Effects of Platelet Agonists and Priming on the Formation of Platelet Populations
por: Veninga, Alicia, et al.
Publicado: (2021)

Mild hyperlipidemia in mice aggravates platelet responsiveness in thrombus formation and exploration of platelet proteome and lipidome
por: van Geffen, Johanna P., et al.
Publicado: (2020)

Multiparameter Evaluation of the Platelet-Inhibitory Effects of Tyrosine Kinase Inhibitors Used for Cancer Treatment
por: Tullemans, Bibian M. E., et al.
Publicado: (2021)

Integrating platelet and coagulation activation in fibrin clot formation
por: Swieringa, Frauke, et al.
Publicado: (2018)

Whole Blood Based Multiparameter Assessment of Thrombus Formation in Standard Microfluidic Devices to Proxy In Vivo Haemostasis and Thrombosis
por: Provenzale, Isabella, et al.
Publicado: (2019)

Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces
por: Jooss, Natalie J., et al.
Publicado: (2019)

Localized endothelial‐based control of platelet aggregation and coagulation under flow: A proof‐of‐principle vessel‐on‐a‐chip study
por: Brouns, Sanne L.N., et al.
Publicado: (2020)

Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integrin inhibitor from ticks
por: van den Kerkhof, Danique L., et al.
Publicado: (2020)

Ultra-high-throughput Ca(2+) assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation
por: Fernández, Delia I., et al.
Publicado: (2021)

Galectin-1 and platelet factor 4 (CXCL4) induce complementary platelet responses in vitro
por: Dickhout, Annemiek, et al.
Publicado: (2021)

GPVI expression is linked to platelet size, age, and reactivity
por: Veninga, Alicia, et al.
Publicado: (2022)

Quantitative and qualitative changes in platelet traits of sunitinib-treated patients with renal cell carcinoma in relation to circulating sunitinib levels: a proof-of-concept study
por: Tullemans, Bibian M. E., et al.
Publicado: (2022)

Tyrosine Kinase Inhibitor Pazopanib Inhibits Platelet Procoagulant Activity in Renal Cell Carcinoma Patients
por: Tullemans, Bibian M. E., et al.
Publicado: (2018)

High-throughput elucidation of thrombus formation reveals sources of platelet function variability
por: van Geffen, Johanna P., et al.
Publicado: (2019)

Stabilizing Role of Platelet P2Y(12) Receptors in Shear-Dependent Thrombus Formation on Ruptured Plaques
por: Nergiz-Unal, Reyhan, et al.
Publicado: (2010)

Temporal Roles of Platelet and Coagulation Pathways in Collagen- and Tissue Factor-Induced Thrombus Formation
por: Navarro, Stefano, et al.
Publicado: (2021)

Fibrin Networks Regulate Protein Transport during Thrombus Development
por: Kim, Oleg V., et al.
Publicado: (2013)

Regulation of Glycoprotein VI-Dependent Platelet Activation and Thrombus Formation by Heparan Sulfate Proteoglycan Perlecan
por: Provenzale, Isabella, et al.
Publicado: (2023)

Platelet Dysfunction in Thrombosis Patients Treated with Vitamin K Antagonists and Recurrent Bleeding
por: van der Meijden, Paola E. J., et al.
Publicado: (2013)

Targeting Human Thrombus by Liposomes Modified with Anti-Fibrin Protein Binders
por: Petroková, Hana, et al.
Publicado: (2019)

Comparison of inhibitory effects of irreversible and reversible Btk inhibitors on platelet function
por: Tullemans, Bibian M.E., et al.
Publicado: (2021)

LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis
por: Kroone, Chantal, et al.
Publicado: (2020)

Comparative Analysis of Microfluidics Thrombus Formation in Multiple Genetically Modified Mice: Link to Thrombosis and Hemostasis
por: Nagy, Magdolna, et al.
Publicado: (2019)

Longitudinal Trend of Plasma Concentrations of Extracellular Vesicles in Patients Hospitalized for COVID-19
por: Campello, Elena, et al.
Publicado: (2022)

Absence of hypercoagulability after nCoV-19 vaccination: An observational pilot study
por: Campello, Elena, et al.
Publicado: (2021)

Impact of Deficiency of Intrinsic Coagulation Factors XI and XII on Ex Vivo Thrombus Formation and Clot Lysis
por: Govers-Riemslag, José W. P., et al.
Publicado: (2019)

Effects of the PAR-1 Antagonist Vorapaxar on Platelet Activation and Coagulation Biomarkers in Patients with Stable Coronary Artery Disease
por: Olie, Renske H., et al.
Publicado: (2019)

Fibrin clot properties and thrombus composition in cirrhosis
por: Driever, Ellen G., et al.
Publicado: (2023)

Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery
por: Mastenbroek, T. G., et al.
Publicado: (2020)

Molecular Mechanisms of Hemostasis, Thrombosis and Thrombo-Inflammation
por: Kuijpers, Marijke J. E., et al.
Publicado: (2022)

Direct Oral Anticoagulants in Patients With Inherited Thrombophilia and Venous Thromboembolism: A Prospective Cohort Study
por: Campello, Elena, et al.
Publicado: (2020)

Assessing Clinically Meaningful Hypercoagulability after COVID-19 Vaccination: A Longitudinal Study
por: Campello, Elena, et al.
Publicado: (2022)

Genetic Analysis of the Role of Protein Kinase Cθ in Platelet Function and Thrombus Formation
por: Hall, Kellie J., et al.
Publicado: (2008)

Functional Divergence of Platelet Protein Kinase C (PKC) Isoforms in Thrombus Formation on Collagen
por: Gilio, Karen, et al.
Publicado: (2010)

Coagulopathy is not predictive of bleeding in patients with acute decompensation of cirrhosis and acute‐on‐chronic liver failure
por: Campello, Elena, et al.
Publicado: (2021)

More Pronounced Hypercoagulable State and Hypofibrinolysis in Patients With Cirrhosis With Versus Without HCC
por: Zanetto, Alberto, et al.
Publicado: (2021)

Role of Tyrosine Kinase Syk in Thrombus Stabilisation at High Shear
por: Perrella, Gina, et al.
Publicado: (2022)

Global hemostatic profiling in patients with decompensated cirrhosis and bacterial infections
por: Zanetto, Alberto, et al.
Publicado: (2022)

Defective fibrin deposition and thrombus stability in Bambi (−/−) mice are mediated by elevated anticoagulant function
por: Crawley, James T. B., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_nnd4bqgav9js8thn627bi1ldif