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Epitope-specific anti-PrP antibody toxicity: a comparative in-silico study of human and mouse prion proteins
Despite having therapeutic potential, anti-PrP antibodies caused a major controversy due to their neurotoxic effects. For instance, treating mice with ICSM antibodies delayed prion disease onset, but both were found to be either toxic or innocuous to neurons by researchers following cross-linking Pr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900626/ https://www.ncbi.nlm.nih.gov/pubmed/34632945 http://dx.doi.org/10.1080/19336896.2021.1964326 |