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Pivotal role of a conserved histidine in Escherichia coli ribonuclease HI as proposed by X-ray crystallography
The ribonuclease (RNase) H family of enzymes catalyze the specific cleavage of RNA strands of RNA/DNA hybrid duplexes and play an important role in DNA replication and repair. Since the first report of the crystal structure of RNase HI, its catalytic mechanisms, which require metal ions, have been d...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900815/ https://www.ncbi.nlm.nih.gov/pubmed/35234152 http://dx.doi.org/10.1107/S2059798322000870 |