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Establishment of a stable SARS-CoV-2 replicon system for application in high-throughput screening

Experiments with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are limited by the need for biosafety level 3 (BSL3) conditions. A SARS-CoV-2 replicon system rather than an in vitro infection system is suitable for antiviral screening since it can be handled under BSL2 conditions and d...

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Detalles Bibliográficos
Autores principales: Tanaka, Tomohisa, Saito, Akatsuki, Suzuki, Tatsuya, Miyamoto, Yoichi, Takayama, Kazuo, Okamoto, Toru, Moriishi, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8900913/
https://www.ncbi.nlm.nih.gov/pubmed/35271914
http://dx.doi.org/10.1016/j.antiviral.2022.105268