How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition

The stochastic expression of fewer than 60 clustered protocadherin (cPcdh) isoforms provides diverse identities to individual vertebrate neurons and a molecular basis for self-/nonself-discrimination. cPcdhs form chains mediated by alternating cis and trans interactions between apposed membranes, wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Goodman, Kerry Marie, Katsamba, Phinikoula S, Rubinstein, Rotem, Ahlsén, Göran, Bahna, Fabiana, Mannepalli, Seetha, Dan, Hanbin, Sampogna, Rosemary V, Shapiro, Lawrence, Honig, Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901172/
https://www.ncbi.nlm.nih.gov/pubmed/35253643
http://dx.doi.org/10.7554/eLife.72416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901172/
https://www.ncbi.nlm.nih.gov/pubmed/35253643
http://dx.doi.org/10.7554/eLife.72416

Ejemplares similares