Safety, Pharmacokinetics and Pharmacodynamics of the Selective Glucocorticoid Receptor Modulator Velsecorat (AZD7594) Following Inhalation in Healthy Volunteers

INTRODUCTION: Velsecorat (AZD7594) is a non-steroidal, selective, glucocorticoid receptor modulator (SGRM), being developed for the treatment of asthma. This article reports the initial, first-in-human, single and repeat dose-escalating study in healthy male volunteers. METHODS: The study comprised...

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Detalles Bibliográficos
Autores principales: Prothon, Susanne, Aurivillius, Magnus, Tehler, Ulrika, Eriksson, Ulf G, Aggarwal, Ajay, Chen, Yingxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901234/
https://www.ncbi.nlm.nih.gov/pubmed/35264846
http://dx.doi.org/10.2147/DDDT.S334960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901234/
https://www.ncbi.nlm.nih.gov/pubmed/35264846
http://dx.doi.org/10.2147/DDDT.S334960

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