Inhibition of neprilysin with sacubitril without RAS blockage aggravates renal disease in Dahl SS rats

Salt-sensitive (SS) hypertension is accompanied with severe cardiorenal complications. In this condition, elevated blood pressure (BP) resulting from salt retention is associated with counterintuitively lower levels of atrial natriuretic peptide (ANP). In plasma, ANP is degraded by the neprilysin; t...

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Detalles Bibliográficos
Autores principales: Polina, Iuliia, Spicer, Morgan J., Domondon, Mark, Schibalski, Ryan S., Sarsenova, Elizaveta, Sultanova, Regina F., Ilatovskaya, Daria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Laboratory Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901277/
https://www.ncbi.nlm.nih.gov/pubmed/33541194
http://dx.doi.org/10.1080/0886022X.2021.1879856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901277/
https://www.ncbi.nlm.nih.gov/pubmed/33541194
http://dx.doi.org/10.1080/0886022X.2021.1879856

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