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UCHL5 controls β-catenin destruction complex function through Axin1 regulation

Wnt/β-catenin signaling is crucially involved in many biological processes, from embryogenesis to cancer development. Hence, the complete understanding of its molecular mechanism has been the biggest challenge in the Wnt research field. Here, we identified ubiquitin C-terminal hydrolase like 5 (UCHL...

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Detalles Bibliográficos
Autores principales: Han, Wonhee, Koo, Youngmu, Chaieb, Leila, Keum, Byeong-Rak, Han, Jin-Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901634/
https://www.ncbi.nlm.nih.gov/pubmed/35256667
http://dx.doi.org/10.1038/s41598-022-07642-1