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mTOR Inhibitors Induce Erythropoietin Resistance in Renal Transplant Recipients

AIM: To elucidate the role of mTOR inhibitors on iron, hepcidin and erythropoietin-mediated regulation of hemopoiesis in stable renal transplant recipients (RTR). BACKGROUND: Impaired hemopoiesis is common following renal transplantation managed using mTOR inhibitors. The mechanisms responsible are...

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Detalles Bibliográficos
Autores principales: Jefferies, Reece, Puttagunta, Harish, Krishnan, Anoushka, Irish, Ashley, Swaminathan, Ramyasuda, Olynyk, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901721/
https://www.ncbi.nlm.nih.gov/pubmed/35273970
http://dx.doi.org/10.3389/fmed.2022.722058