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Link between the EZH2 noncanonical pathway and microtubule organization center polarization during early T lymphopoiesis

EZH2 plays an essential role at the β-selection checkpoint of T lymphopoiesis by regulating histone H3 lysine 27 trimethylation (H3K27me3) via its canonical mode of action. Increasing data suggest that EZH2 could also regulate other cellular functions, such as cytoskeletal reorganization, via its no...

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Detalles Bibliográficos
Autores principales: Deshayes, Frederique, Fradet, Magali, Kaminski, Sandra, Viguier, Mireille, Frippiat, Jean-Pol, Ghislin, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901749/
https://www.ncbi.nlm.nih.gov/pubmed/35256668
http://dx.doi.org/10.1038/s41598-022-07684-5