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Nectin cell adhesion molecule 4 regulates angiogenesis through Src signaling and serves as a novel therapeutic target in angiosarcoma

Angiosarcoma is a rare, life-threatening soft tissue sarcoma with malignant endothelial cells that is mainly found in the skin. Multidisciplinary approaches are used to treat patients with unresectable metastasized lesions; considering the cellular origin of angiosarcoma, anti-angiogenic therapy has...

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Detalles Bibliográficos
Autores principales: Tanaka, Yuka, Murata, Maho, Tanegashima, Keiko, Oda, Yoshinao, Ito, Takamichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901754/
https://www.ncbi.nlm.nih.gov/pubmed/35256687
http://dx.doi.org/10.1038/s41598-022-07727-x