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Single cell-derived spheroids capture the self-renewing subpopulations of metastatic ovarian cancer

High Grade Serous Ovarian cancer (HGSOC) is a major unmet need in oncology, due to its precocious dissemination and the lack of meaningful human models for the investigation of disease pathogenesis in a patient-specific manner. To overcome this roadblock, we present a new method to isolate and grow...

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Detalles Bibliográficos
Autores principales: Velletri, Tania, Villa, Carlo Emanuele, Cilli, Domenica, Barzaghi, Bianca, Lo Riso, Pietro, Lupia, Michela, Luongo, Raffaele, López-Tobón, Alejandro, De Simone, Marco, Bonnal, Raoul J. P., Marelli, Luca, Piccolo, Stefano, Colombo, Nicoletta, Pagani, Massimiliano, Cavallaro, Ugo, Minucci, Saverio, Testa, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901794/
https://www.ncbi.nlm.nih.gov/pubmed/34845371
http://dx.doi.org/10.1038/s41418-021-00878-w