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Hypoxia-induced PVT1 promotes lung cancer chemoresistance to cisplatin by autophagy via PVT1/miR-140-3p/ATG5 axis

Lung cancer is one of the most common and lethal malignant tumors and the cases increased rapidly. Elevated chemoresistance during chemotherapy resistance remains a challenge. Hypoxia is one of the components that lead to chemoresistance. PVT1 participates in various tumor drug resistance and is ass...

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Detalles Bibliográficos
Autores principales: Wang, Jiying, Dong, Zhiyi, Sheng, Zhaoying, Cai, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901807/
https://www.ncbi.nlm.nih.gov/pubmed/35256612
http://dx.doi.org/10.1038/s41420-022-00886-w