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Reducing N6AMT1-mediated 6mA DNA modification promotes breast tumor progression via transcriptional repressing cell cycle inhibitors

DNA N6-methyladenosine (6mA) is a novel epigenetic signaling modification in humans and has been implicated in the progression and tumorigenesis of several cancers. However, the function and mechanism of 6mA in breast cancer (BC), the most common cancer among women, are unclear. Here, we found that...

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Detalles Bibliográficos
Autores principales: Chen, Jiongyu, Zhuang, Yixuan, Wang, Ping, Ning, Jinfeng, Liu, Wei, Huang, Yiteng, Lin, Xueqiong, Peng, Lin, Zhang, Donghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901905/
https://www.ncbi.nlm.nih.gov/pubmed/35256595
http://dx.doi.org/10.1038/s41419-022-04661-8