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Reducing N6AMT1-mediated 6mA DNA modification promotes breast tumor progression via transcriptional repressing cell cycle inhibitors
DNA N6-methyladenosine (6mA) is a novel epigenetic signaling modification in humans and has been implicated in the progression and tumorigenesis of several cancers. However, the function and mechanism of 6mA in breast cancer (BC), the most common cancer among women, are unclear. Here, we found that...
Autores principales: | Chen, Jiongyu, Zhuang, Yixuan, Wang, Ping, Ning, Jinfeng, Liu, Wei, Huang, Yiteng, Lin, Xueqiong, Peng, Lin, Zhang, Donghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901905/ https://www.ncbi.nlm.nih.gov/pubmed/35256595 http://dx.doi.org/10.1038/s41419-022-04661-8 |
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