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Spatially Annotated Single Cell Sequencing for Unraveling Intratumor Heterogeneity

Intratumor heterogeneity is a major obstacle to effective cancer treatment. Current methods to study intratumor heterogeneity using single-cell RNA sequencing (scRNA-seq) lack information on the spatial organization of cells. While state-of-the art spatial transcriptomics methods capture the spatial...

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Detalles Bibliográficos
Autores principales:	Smit, Myrthe M., Feller, Kate J., You, Li, Storteboom, Jelle, Begce, Yasin, Beerens, Cecile, Chien, Miao-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902076/ https://www.ncbi.nlm.nih.gov/pubmed/35273957 http://dx.doi.org/10.3389/fbioe.2022.829509

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