Spatially Annotated Single Cell Sequencing for Unraveling Intratumor Heterogeneity
Intratumor heterogeneity is a major obstacle to effective cancer treatment. Current methods to study intratumor heterogeneity using single-cell RNA sequencing (scRNA-seq) lack information on the spatial organization of cells. While state-of-the art spatial transcriptomics methods capture the spatial...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902076/ https://www.ncbi.nlm.nih.gov/pubmed/35273957 http://dx.doi.org/10.3389/fbioe.2022.829509 |