CPT1A-Mediated Fatty Acid Oxidation Promotes Precursor Osteoclast Fusion in Rheumatoid Arthritis

The overproduction of osteoclasts, leading to bone destruction in patients with rheumatoid arthritis (RA), is well established. However, little is known about the metabolic dysfunction of osteoclast precursors (OCPs) in RA. Herein, we show that increasing fatty acid oxidation (FAO) induces OCP fusio...

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Detalles Bibliográficos
Autores principales: Huang, Zhaoyang, Luo, Rong, Yang, Liu, Chen, Haiqi, Zhang, Xinyao, Han, Jiawen, Wang, Hongxia, Zhou, Zhongyang, Wang, Zhao, Shao, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902079/
https://www.ncbi.nlm.nih.gov/pubmed/35273614
http://dx.doi.org/10.3389/fimmu.2022.838664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902079/
https://www.ncbi.nlm.nih.gov/pubmed/35273614
http://dx.doi.org/10.3389/fimmu.2022.838664

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