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CPT1A-Mediated Fatty Acid Oxidation Promotes Precursor Osteoclast Fusion in Rheumatoid Arthritis
The overproduction of osteoclasts, leading to bone destruction in patients with rheumatoid arthritis (RA), is well established. However, little is known about the metabolic dysfunction of osteoclast precursors (OCPs) in RA. Herein, we show that increasing fatty acid oxidation (FAO) induces OCP fusio...
Autores principales: | Huang, Zhaoyang, Luo, Rong, Yang, Liu, Chen, Haiqi, Zhang, Xinyao, Han, Jiawen, Wang, Hongxia, Zhou, Zhongyang, Wang, Zhao, Shao, Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902079/ https://www.ncbi.nlm.nih.gov/pubmed/35273614 http://dx.doi.org/10.3389/fimmu.2022.838664 |
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