Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges

A virosomal vaccine inducing systemic/mucosal anti-HIV-1 gp41 IgG/IgA had previously protected Chinese-origin rhesus macaques (RMs) against vaginal SHIV(SF162P3) challenges. Here, we assessed its efficacy in Indian-origin RMs by intramuscular priming/intranasal boosting (n=12/group). Group K receive...

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Detalles Bibliográficos
Autores principales: Lakhashe, Samir K., Amacker, Mario, Hariraju, Dinesh, Vyas, Hemant K., Morrison, Kyle S., Weiner, Joshua A., Ackerman, Margaret E., Roy, Vicky, Alter, Galit, Ferrari, Guido, Montefiori, David C., Tomaras, Georgia D., Sawant, Sheetal, Yates, Nicole L., Gast, Chris, Fleury, Sylvain, Ruprecht, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902080/
https://www.ncbi.nlm.nih.gov/pubmed/35273592
http://dx.doi.org/10.3389/fimmu.2022.788619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902080/
https://www.ncbi.nlm.nih.gov/pubmed/35273592
http://dx.doi.org/10.3389/fimmu.2022.788619

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