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Exosomal miR-29b of Gut Origin in Patients With Ulcerative Colitis Suppresses Heart Brain-Derived Neurotrophic Factor

Background and Aims: While the interplay between heart and gut in inflammatory bowel disease (IBD) has previously been noted, how the inflamed gut impairs heart function remain elusive. We hypothesized that exosomal miRNAs of gut origin induce cardiac remodeling in IBD. Our aim was to identify plasm...

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Detalles Bibliográficos
Autores principales: Lian, Haifeng, Zhong, Xiaoying S., Xiao, Ying, Sun, Zhe, Shen, Yuanyuan, Zhao, Kaile, Ma, Xingbin, Li, Yanmin, Niu, Qiong, Liu, Max, Powell, Don W., Liu, Chengxia, Li, Qingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902158/
https://www.ncbi.nlm.nih.gov/pubmed/35274002
http://dx.doi.org/10.3389/fmolb.2022.759689