Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation

Doxorubicin (DOX) is an anthracycline antibiotic that is used extensively for the management of carcinoma; however, its clinical application is limited due to its serious cardiotoxic side effects. Ferroptosis represents iron-dependent and reactive oxygen species (ROS)-related cell death and has been...

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Detalles Bibliográficos
Autores principales: Li, Danlei, Liu, Xiaoman, Pi, Wenhu, Zhang, Yang, Yu, Lei, Xu, Cheng, Sun, Zhenzhu, Jiang, Jianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902236/
https://www.ncbi.nlm.nih.gov/pubmed/35273493
http://dx.doi.org/10.3389/fphar.2021.808480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902236/
https://www.ncbi.nlm.nih.gov/pubmed/35273493
http://dx.doi.org/10.3389/fphar.2021.808480

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