Cargando…

Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation

Doxorubicin (DOX) is an anthracycline antibiotic that is used extensively for the management of carcinoma; however, its clinical application is limited due to its serious cardiotoxic side effects. Ferroptosis represents iron-dependent and reactive oxygen species (ROS)-related cell death and has been...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Danlei, Liu, Xiaoman, Pi, Wenhu, Zhang, Yang, Yu, Lei, Xu, Cheng, Sun, Zhenzhu, Jiang, Jianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902236/ https://www.ncbi.nlm.nih.gov/pubmed/35273493 http://dx.doi.org/10.3389/fphar.2021.808480

Ejemplares similares

Post-treatment With Irisin Attenuates Acute Kidney Injury in Sepsis Mice Through Anti-Ferroptosis via the SIRT1/Nrf2 Pathway
por: Qiongyue, Zhang, et al.
Publicado: (2022)

Icariin Ameliorates Diabetic Cardiomyopathy Through Apelin/Sirt3 Signalling to Improve Mitochondrial Dysfunction
por: Ni, Tingjuan, et al.
Publicado: (2020)

Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome
por: Dong, Wenmin, et al.
Publicado: (2022)

Fisetin Attenuated Oxidative Stress-Induced Cellular Damage in ARPE-19 Human Retinal Pigment Epithelial Cells Through Nrf2-Mediated Activation of Heme Oxygenase-1
por: Park, Cheol, et al.
Publicado: (2022)

Daphnetin Attenuated Cisplatin-Induced Acute Nephrotoxicity With Enhancing Antitumor Activity of Cisplatin by Upregulating SIRT1/SIRT6-Nrf2 Pathway
por: Fan, Xiaoye, et al.
Publicado: (2020)

Isoorientin Attenuates Cisplatin-Induced Nephrotoxicity Through the Inhibition of Oxidative Stress and Apoptosis via Activating the SIRT1/SIRT6/Nrf-2 Pathway
por: Fan, Xiaoye, et al.
Publicado: (2020)

2′-O-Galloylhyperin Isolated From Pyrola incarnata Fisch. Attenuates LPS-Induced Inflammatory Response by Activation of SIRT1/Nrf2 and Inhibition of the NF-κB Pathways in Vitro and Vivo
por: Wang, Peng, et al.
Publicado: (2018)

Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway
por: Liu, Zhuanghua, et al.
Publicado: (2022)

Fisetin Attenuates Myocardial Ischemia-Reperfusion Injury by Activating the Reperfusion Injury Salvage Kinase (RISK) Signaling Pathway
por: Shanmugam, Karthi, et al.
Publicado: (2021)

SGLT1 Inhibition Attenuates Apoptosis in Diabetic Cardiomyopathy via the JNK and p38 Pathway
por: Lin, Na, et al.
Publicado: (2021)

Fisetin Prevents Acetaminophen-Induced Liver Injury by Promoting Autophagy
por: Zhang, Jiaqi, et al.
Publicado: (2020)

Fisetin: An Integrated Approach to Identify a Strategy Promoting Osteogenesis
por: Dalle Carbonare, Luca, et al.
Publicado: (2022)

Doxorubicin cardiomyopathy is ameliorated by acacetin via Sirt1‐mediated activation of AMPK/Nrf2 signal molecules
por: Wu, Wei‐Yin, et al.
Publicado: (2020)

Targeting ferroptosis as a promising therapeutic strategy to treat cardiomyopathy
por: Sun, Huiyan, et al.
Publicado: (2023)

Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway
por: Guo, Zhou, et al.
Publicado: (2022)

Curcumin Attenuates Ferroptosis-Induced Myocardial Injury in Diabetic Cardiomyopathy through the Nrf2 Pathway
por: Wei, Zhang, et al.
Publicado: (2022)

Dimethyl Fumarate Ameliorates Doxorubicin-Induced Cardiotoxicity By Activating the Nrf2 Pathway
por: Hu, Xiaoliang, et al.
Publicado: (2022)

Corrigendum: Deferoxamine alleviates osteoarthritis by inhibiting chondrocyte ferroptosis and activating the Nrf2 pathway
por: Guo, Zhou, et al.
Publicado: (2023)

Urolithin A (UA) attenuates ferroptosis in LPS-induced acute lung injury in mice by upregulating Keap1-Nrf2/HO-1 signaling pathway
por: Lou, Lejing, et al.
Publicado: (2023)

SIRT6 Activator UBCS039 Inhibits Thioacetamide-Induced Hepatic Injury In Vitro and In Vivo
por: Jiao, Fangzhou, et al.
Publicado: (2022)

Omaveloxolone inhibits IL-1β-induced chondrocyte apoptosis through the Nrf2/ARE and NF-κB signalling pathways in vitro and attenuates osteoarthritis in vivo
por: Jiang, Zengxin, et al.
Publicado: (2022)

Formulation development of lipid polymer hybrid nanoparticles of doxorubicin and its in-vitro, in-vivo and computational evaluation
por: Shafique, Muhammad, et al.
Publicado: (2023)

Raltegravir Attenuates Experimental Pulmonary Fibrosis In Vitro and In Vivo
por: Zhang, Xue, et al.
Publicado: (2019)

Gabapentin Attenuates Ocular Inflammation: In vitro and In vivo Studies
por: Anfuso, Carmelina D., et al.
Publicado: (2017)

Cariporide Attenuates Doxorubicin-Induced Cardiotoxicity in Rats by Inhibiting Oxidative Stress, Inflammation and Apoptosis Partly Through Regulation of Akt/GSK-3β and Sirt1 Signaling Pathway
por: Liao, Wenli, et al.
Publicado: (2022)

Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis
por: Liu, Xing, et al.
Publicado: (2023)

SIRT1 activation and its effect on intercalated disc proteins as a way to reduce doxorubicin cardiotoxicity
por: Podyacheva, Ekaterina, et al.
Publicado: (2022)

Geniposide Alleviates Isoproterenol-Induced Cardiac Fibrosis Partially via SIRT1 Activation in vivo and in vitro
por: Li, Ning, et al.
Publicado: (2018)

Protective effect of cafestol against doxorubicin-induced cardiotoxicity in rats by activating the Nrf2 pathway
por: Al-Kenany, Sara A., et al.
Publicado: (2023)

Melatonin Restores Autophagic Flux by Activating the Sirt3/TFEB Signaling Pathway to Attenuate Doxorubicin-Induced Cardiomyopathy
por: Ma, Yanyan, et al.
Publicado: (2023)

The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
por: Hassan, Syed Shams ul, et al.
Publicado: (2022)

Formononetin Activates the Nrf2/ARE Signaling Pathway Via Sirt1 to Improve Diabetic Renal Fibrosis
por: Zhuang, Kai, et al.
Publicado: (2021)

Erratum: SIRT1 activation and its effect on intercalated disc proteins as a way to reduce doxorubicin cardiotoxicity
por: Frontiers Production Office,
Publicado: (2023)

EP1 activation inhibits doxorubicin-cardiomyocyte ferroptosis via Nrf2
por: Wang, Bei, et al.
Publicado: (2023)

MST1 mediates doxorubicin-induced cardiomyopathy by SIRT3 downregulation
por: Schirone, Leonardo, et al.
Publicado: (2023)

Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence
por: Zhang, Li, et al.
Publicado: (2020)

Fisetin Rescues the Mice Brains Against D-Galactose-Induced Oxidative Stress, Neuroinflammation and Memory Impairment
por: Ahmad, Sareer, et al.
Publicado: (2021)

Corrigendum: The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
por: Hassan, Syed Shams ul, et al.
Publicado: (2022)

Natural Product Erianin Inhibits Bladder Cancer Cell Growth by Inducing Ferroptosis via NRF2 Inactivation
por: Xiang, Yu, et al.
Publicado: (2021)

Glabridin Attenuates the Retinal Degeneration Induced by Sodium Iodate In Vitro and In Vivo
por: Aung, Kaung Htet, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gsn0ftu37qtu4p0gun6o5omvrb