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A Quantitative Approach to Unravel the Role of Host Genetics in IgG-FcγR Complex Formation After Vaccination

Fc-mediated immune functions have been correlated with protection in the RV144 HIV vaccine trial and are important for immunity to a range of pathogens. IgG antibodies (Abs) that form complexes with Fc receptors (FcRs) on innate immune cells can activate Fc-mediated immune functions. Genetic variati...

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Detalles Bibliográficos
Autores principales: Lemke, Melissa M., Theisen, Robert M., Bozich, Emily R., McLean, Milla R., Lee, Christina Y., Lopez, Ester, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Nitayaphan, Sorachai, Kratochvil, Sven, Wines, Bruce D., Hogarth, P. Mark, Kent, Stephen J., Chung, Amy W., Arnold, Kelly B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902241/
https://www.ncbi.nlm.nih.gov/pubmed/35273603
http://dx.doi.org/10.3389/fimmu.2022.820148