ECM Depletion Is Required to Improve the Intratumoral Uptake of Iron Oxide Nanoparticles in Poorly Perfused Hepatocellular Carcinoma

Improving tumor access for drug delivery is challenging, particularly in poorly perfused tumors. The availability of functional tumor blood vessels for systemic access is vital to allow drugs or imaging agents to accumulate in the tumor parenchyma. We subjected mice engineered to develop hepatocellu...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeow, Yen Ling, Wu, Jiansha, Wang, Xiao, Winteringham, Louise, Feindel, Kirk W., Tirnitz-Parker, Janina E. E., Leedman, Peter J., Ganss, Ruth, Hamzah, Juliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902243/
https://www.ncbi.nlm.nih.gov/pubmed/35273916
http://dx.doi.org/10.3389/fonc.2022.837234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902243/
https://www.ncbi.nlm.nih.gov/pubmed/35273916
http://dx.doi.org/10.3389/fonc.2022.837234

Ejemplares similares