Adapalene Inhibits Prostate Cancer Cell Proliferation In Vitro and In Vivo by Inducing DNA Damage, S-phase Cell Cycle Arrest, and Apoptosis

Aims: Prostate cancer is a well-known aggressive malignant tumor in men with a high metastasis rate and poor prognosis. Adapalene (ADA) is a third-generation synthetic retinoid with anticancer properties. We investigated the anti-tumor activity and molecular mechanisms of ADA in the RM-1 prostate ca...

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Detalles Bibliográficos
Autores principales: Nong, Hai-bin, Zhang, Ya-nan, Bai, Yi-guang, Zhang, Qiong, Liu, Ming-fu, Zhou, Quan, Shi, Zhuo-hua, Zeng, Gao-feng, Zong, Shao-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902295/
https://www.ncbi.nlm.nih.gov/pubmed/35273495
http://dx.doi.org/10.3389/fphar.2022.801624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902295/
https://www.ncbi.nlm.nih.gov/pubmed/35273495
http://dx.doi.org/10.3389/fphar.2022.801624

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