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Effects of eicosapentaenoic acid on serum levels of selenoprotein P and organ‐specific insulin sensitivity in humans with dyslipidemia and type 2 diabetes

AIM: Selenoprotein P (SeP, encoded by SELENOP in humans) is a hepatokine that causes insulin resistance in the liver and skeletal muscle. It was found that polyunsaturated fatty acid eicosapentaenoic acid (EPA) downregulates Selenop expression by inactivating SREBP‐1c. The present study aimed to exa...

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Detalles Bibliográficos
Autores principales: Takeshita, Yumie, Teramura, Chisato, Kamoshita, Kyoko, Takayama, Hiroaki, Nakagawa, Hiromi, Enyama, Yasufumi, Ishii, Kiyo‐Aki, Tanaka, Takeo, Goto, Hisanori, Nakano, Yujiro, Osada, Sachie, Tanaka, Yoshiaki, Tokuyama, Kumpei, Takamura, Toshinari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902388/
https://www.ncbi.nlm.nih.gov/pubmed/34670012
http://dx.doi.org/10.1111/jdi.13699