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Effects of eicosapentaenoic acid on serum levels of selenoprotein P and organ‐specific insulin sensitivity in humans with dyslipidemia and type 2 diabetes
AIM: Selenoprotein P (SeP, encoded by SELENOP in humans) is a hepatokine that causes insulin resistance in the liver and skeletal muscle. It was found that polyunsaturated fatty acid eicosapentaenoic acid (EPA) downregulates Selenop expression by inactivating SREBP‐1c. The present study aimed to exa...
Autores principales: | Takeshita, Yumie, Teramura, Chisato, Kamoshita, Kyoko, Takayama, Hiroaki, Nakagawa, Hiromi, Enyama, Yasufumi, Ishii, Kiyo‐Aki, Tanaka, Takeo, Goto, Hisanori, Nakano, Yujiro, Osada, Sachie, Tanaka, Yoshiaki, Tokuyama, Kumpei, Takamura, Toshinari |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902388/ https://www.ncbi.nlm.nih.gov/pubmed/34670012 http://dx.doi.org/10.1111/jdi.13699 |
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