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Low-dose azathioprine and allopurinol versus azathioprine monotherapy in patients with ulcerative colitis (AAUC): An investigator-initiated, open, multicenter, parallel-arm, randomised controlled trial

BACKGROUND: Retrospective studies suggest that for patients with ulcerative colitis (UC) combination therapy with low-dose azathioprine and allopurinol (L-AZA/ALLO) may result in higher remission rates than monotherapy with azathioprine (AZA). We prospectively investigated the effects of these drugs...

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Detalles Bibliográficos
Autores principales: Kiszka-Kanowitz, Marianne, Theede, Klaus, Thomsen, Sandra Bohn, Bjerrum, Jacob Tveiten, Brynskov, Jørn, Gottschalck, Ida Benedikte, Akimenko, Elena, Hilsted, Karen Lisa, Neumann, Anders, Wildt, Signe, Larsen, Lone, Munk, Jens Kristian, Ibsen, Per Holger, Janjua, Huma Gul Rehana, Gluud, Lise Lotte, Mertz-Nielsen, Anette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902607/
https://www.ncbi.nlm.nih.gov/pubmed/35274092
http://dx.doi.org/10.1016/j.eclinm.2022.101332