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Low-dose azathioprine and allopurinol versus azathioprine monotherapy in patients with ulcerative colitis (AAUC): An investigator-initiated, open, multicenter, parallel-arm, randomised controlled trial
BACKGROUND: Retrospective studies suggest that for patients with ulcerative colitis (UC) combination therapy with low-dose azathioprine and allopurinol (L-AZA/ALLO) may result in higher remission rates than monotherapy with azathioprine (AZA). We prospectively investigated the effects of these drugs...
Autores principales: | Kiszka-Kanowitz, Marianne, Theede, Klaus, Thomsen, Sandra Bohn, Bjerrum, Jacob Tveiten, Brynskov, Jørn, Gottschalck, Ida Benedikte, Akimenko, Elena, Hilsted, Karen Lisa, Neumann, Anders, Wildt, Signe, Larsen, Lone, Munk, Jens Kristian, Ibsen, Per Holger, Janjua, Huma Gul Rehana, Gluud, Lise Lotte, Mertz-Nielsen, Anette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902607/ https://www.ncbi.nlm.nih.gov/pubmed/35274092 http://dx.doi.org/10.1016/j.eclinm.2022.101332 |
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