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A lysine-rich cluster in the N-BAR domain of ARF GTPase-activating protein ASAP1 is necessary for binding and bundling actin filaments

Actin filament maintenance is critical for both normal cell homeostasis and events associated with malignant transformation. The ADP-ribosylation factor GTPase-activating protein ASAP1 regulates the dynamics of filamentous actin-based structures, including stress fibers, focal adhesions, and circula...

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Detalles Bibliográficos
Autores principales: Gasilina, Anjelika, Yoon, Hye-Young, Jian, Xiaoying, Luo, Ruibai, Randazzo, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902617/
https://www.ncbi.nlm.nih.gov/pubmed/35143843
http://dx.doi.org/10.1016/j.jbc.2022.101700