The carboxyl-terminal region of SDCCAG8 comprises a functional module essential for cilia formation as well as organ development and homeostasis

In humans, ciliary dysfunction causes ciliopathies, which present as multiple organ defects, including developmental and sensory abnormalities. Sdccag8 is a centrosomal/basal body protein essential for proper cilia formation. Gene mutations in SDCCAG8 have been found in patients with ciliopathies ma...

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Detalles Bibliográficos
Autores principales: Tsutsumi, Ryotaro, Chaya, Taro, Tsujii, Toshinori, Furukawa, Takahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902618/
https://www.ncbi.nlm.nih.gov/pubmed/35131266
http://dx.doi.org/10.1016/j.jbc.2022.101686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902618/
https://www.ncbi.nlm.nih.gov/pubmed/35131266
http://dx.doi.org/10.1016/j.jbc.2022.101686

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