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Oligomerization of DNA replication regulatory protein RADX is essential to maintain replication fork stability

Genome integrity requires complete and accurate DNA replication once per cell division cycle. Replication stress poses obstacles to this process that must be overcome to prevent replication fork collapse. An important regulator of replication fork stability is the RAD51 protein, which promotes repli...

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Detalles Bibliográficos
Autores principales: Mohamed, Taha, Adolph, Madison B., Cortez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902620/
https://www.ncbi.nlm.nih.gov/pubmed/35120927
http://dx.doi.org/10.1016/j.jbc.2022.101672