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CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells

Costimulation pathways play an essential role in T cell activation, differentiation, and regulation. CD155 expressed on antigen-presenting cells (APCs) interacts with TIGIT, an inhibitory costimulatory molecule, and CD226, an activating costimulatory molecule, on T cells. TIGIT and CD226 are express...

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Detalles Bibliográficos
Autores principales: Yasutomi, Motoko, Christiaansen, Allison F., Imai, Naoko, Martin-Orozco, Natalia, Forst, Christian V., Chen, Gang, Ueno, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902812/
https://www.ncbi.nlm.nih.gov/pubmed/35273617
http://dx.doi.org/10.3389/fimmu.2022.840457