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CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells
Costimulation pathways play an essential role in T cell activation, differentiation, and regulation. CD155 expressed on antigen-presenting cells (APCs) interacts with TIGIT, an inhibitory costimulatory molecule, and CD226, an activating costimulatory molecule, on T cells. TIGIT and CD226 are express...
Autores principales: | Yasutomi, Motoko, Christiaansen, Allison F., Imai, Naoko, Martin-Orozco, Natalia, Forst, Christian V., Chen, Gang, Ueno, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902812/ https://www.ncbi.nlm.nih.gov/pubmed/35273617 http://dx.doi.org/10.3389/fimmu.2022.840457 |
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