Cargando…

Plasmodium falciparum GBP2 Is a Telomere-Associated Protein That Binds to G-Quadruplex DNA and RNA

In the early-diverging protozoan parasite Plasmodium, few telomere-binding proteins have been identified and several are unique. Plasmodium telomeres, like those of most eukaryotes, contain guanine-rich repeats that can form G-quadruplex structures. In model systems, quadruplex-binding drugs can dis...

Descripción completa

Detalles Bibliográficos
Autores principales: Edwards-Smallbone, James, Jensen, Anders L., Roberts, Lydia E., Totañes, Francis Isidore G., Hart, Sarah R., Merrick, Catherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902816/
https://www.ncbi.nlm.nih.gov/pubmed/35273922
http://dx.doi.org/10.3389/fcimb.2022.782537