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Plasmodium falciparum GBP2 Is a Telomere-Associated Protein That Binds to G-Quadruplex DNA and RNA
In the early-diverging protozoan parasite Plasmodium, few telomere-binding proteins have been identified and several are unique. Plasmodium telomeres, like those of most eukaryotes, contain guanine-rich repeats that can form G-quadruplex structures. In model systems, quadruplex-binding drugs can dis...
Autores principales: | Edwards-Smallbone, James, Jensen, Anders L., Roberts, Lydia E., Totañes, Francis Isidore G., Hart, Sarah R., Merrick, Catherine J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902816/ https://www.ncbi.nlm.nih.gov/pubmed/35273922 http://dx.doi.org/10.3389/fcimb.2022.782537 |
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