Lack of antiviral activity of probenecid in Vero E6 cells and Syrian golden hamsters: a need for better understanding of inter-lab differences in preclinical assays

Antiviral interventions are urgently required to support vaccination programmes and reduce the global burden of COVID-19. Prior to initiation of large-scale clinical trials, robust preclinical data in support of candidate plausibility are required. The speed at which preclinical models have been dev...

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Detalles Bibliográficos
Autores principales: Box, Helen, Pennington, Shaun H, Kijak, Edyta, Tatham, Lee, Caygill, Claire H, Lopeman, Rose C, Jeffreys, Laura N, Herriott, Joanne, Sharp, Joanne, Neary, Megan, Valentijn, Anthony, Pertinez, Henry, Curley, Paul, Arshad, Usman, Rajoli, Rajith KR, Rannard, Steve, Stewart, James P., Biagini, Giancarlo A, Owen, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902890/
https://www.ncbi.nlm.nih.gov/pubmed/35262084
http://dx.doi.org/10.1101/2022.03.03.482788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902890/
https://www.ncbi.nlm.nih.gov/pubmed/35262084
http://dx.doi.org/10.1101/2022.03.03.482788

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