Energy landscape of the SARS-CoV-2 reveals extensive conformational heterogeneity

Cryo-electron microscopy (cryo-EM) has produced a number of structural models of the SARS-CoV-2 spike, already prompting biomedical outcomes. However, these reported models and their associated electrostatic potential maps represent an unknown admixture of conformations stemming from the underlying...

Descripción completa

Detalles Bibliográficos
Autores principales: Mashayekhi, Ghoncheh, Vant, John, Polavarapu, Abhigna, Ourmazd, Abbas, Singharoy, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902891/
https://www.ncbi.nlm.nih.gov/pubmed/35284830
http://dx.doi.org/10.1016/j.crstbi.2022.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902891/
https://www.ncbi.nlm.nih.gov/pubmed/35284830
http://dx.doi.org/10.1016/j.crstbi.2022.02.001

Ejemplares similares