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Elevated mid-pregnancy plasma levels of angiotensin-converting enzyme 2 in women prior to the development of preeclampsia

Preeclampsia and cardiovascular disease (CVD) share multiple features and risk factors. Circulating angiotensin-converting enzyme 2 (ACE2) is increased in CVD and mediates SARS-CoV-2 entry into host cells, causing COVID-19 infection. The role of ACE2 in preeclampsia pathophysiology is unknown. We hy...

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Detalles Bibliográficos
Autores principales: Junus, Katja, Björk Ragnarsdóttir, Inger, Nordlöf Callbo, Paliz, Bergman, Lina, Lager, Susanne, Wikström, Anna-Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8902901/
https://www.ncbi.nlm.nih.gov/pubmed/35260736
http://dx.doi.org/10.1038/s41598-022-08081-8