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TLR9 Sensing of Self-DNA Controls Cell-Mediated Immunity to Listeria Infection via Rapid Conversion of Conventional CD4(+) T Cells to T(reg)
CD4(+) T lymphocytes are crucial for controlling a range of innate and adaptive immune effectors. For CD8(+) cytotoxic T lymphocyte (CTL) responses, CD4(+) T cells can function as helpers (T(H)) to amplify magnitude and functionality or as regulatory cells (T(reg)) capable of profound inhibition. It...
Autores principales: | Dolina, Joseph S., Lee, Joey, Griswold, Ryan Q., Labarta-Bajo, Lara, Kannan, Sumetha, Greenbaum, Jason A., El Idrissi, Nawal Bahia, Pont, Margot J., Croft, Michael, Schoenberger, Stephen P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903023/ https://www.ncbi.nlm.nih.gov/pubmed/32268093 http://dx.doi.org/10.1016/j.celrep.2020.01.040 |
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