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Natural killer cells kill extracellular Pseudomonas aeruginosa using contact-dependent release of granzymes B and H

Pseudomonas aeruginosa is an opportunistic pathogen that often infects individuals with the genetic disease cystic fibrosis, and contributes to airway blockage and loss of lung function. Natural killer (NK) cells are cytotoxic, granular lymphocytes that are part of the innate immune system. NK cell...

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Detalles Bibliográficos
Autores principales: Feehan, David D., Jamil, Khusraw, Polyak, Maria J., Ogbomo, Henry, Hasell, Mark, LI, Shu Shun, Xiang, Richard F., Parkins, Michael, Trapani, Joseph A., Harrison, Joe J., Mody, Christopher H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903247/
https://www.ncbi.nlm.nih.gov/pubmed/35202434
http://dx.doi.org/10.1371/journal.ppat.1010325