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Cardiac specific knock-down of peroxisome proliferator activated receptor α prevents fasting-induced cardiac lipid accumulation and reduces perilipin 2

While fatty acid metabolism is altered under physiological conditions, alterations can also be maladaptive in diseases such as diabetes and heart failure. Peroxisome Proliferator Activated Receptor α (PPARα) is a transcription factor that regulates fat metabolism but its role in regulating lipid sto...

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Detalles Bibliográficos
Autores principales: Fillmore, Natasha, Hou, Vincent, Sun, Junhui, Springer, Danielle, Murphy, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903264/
https://www.ncbi.nlm.nih.gov/pubmed/35259201
http://dx.doi.org/10.1371/journal.pone.0265007