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Cardiac specific knock-down of peroxisome proliferator activated receptor α prevents fasting-induced cardiac lipid accumulation and reduces perilipin 2
While fatty acid metabolism is altered under physiological conditions, alterations can also be maladaptive in diseases such as diabetes and heart failure. Peroxisome Proliferator Activated Receptor α (PPARα) is a transcription factor that regulates fat metabolism but its role in regulating lipid sto...
Autores principales: | Fillmore, Natasha, Hou, Vincent, Sun, Junhui, Springer, Danielle, Murphy, Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903264/ https://www.ncbi.nlm.nih.gov/pubmed/35259201 http://dx.doi.org/10.1371/journal.pone.0265007 |
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