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Reduced IFN-ß inhibitory activity of Lagos bat virus phosphoproteins in human compared to Eidolon helvum bat cells

Eidolon helvum bats are reservoir hosts for highly pathogenic lyssaviruses often showing limited disease upon natural infection. An enhanced antiviral interferon (IFN) response combined with reduced inflammation might be linked to the apparent virus tolerance in bats. Lyssavirus phosphoproteins inhi...

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Detalles Bibliográficos
Autores principales: Papies, Jan, Sieberg, Andrea, Ritz, Daniel, Niemeyer, Daniela, Drosten, Christian, Müller, Marcel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903296/
https://www.ncbi.nlm.nih.gov/pubmed/35259191
http://dx.doi.org/10.1371/journal.pone.0264450