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Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing

The mRNA 5’ cap structure serves both to protect transcripts from degradation and promote their translation. Cap removal is thus an integral component of mRNA turnover that is carried out by cellular decapping enzymes, whose activity is tightly regulated and coupled to other stages of the mRNA decay...

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Detalles Bibliográficos
Autores principales: Ly, Michael, Burgess, Hannah M., Shah, Sahil B., Mohr, Ian, Glaunsinger, Britt A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903303/
https://www.ncbi.nlm.nih.gov/pubmed/35202449
http://dx.doi.org/10.1371/journal.ppat.1010099