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Vaccinia virus D10 has broad decapping activity that is regulated by mRNA splicing
The mRNA 5’ cap structure serves both to protect transcripts from degradation and promote their translation. Cap removal is thus an integral component of mRNA turnover that is carried out by cellular decapping enzymes, whose activity is tightly regulated and coupled to other stages of the mRNA decay...
Autores principales: | Ly, Michael, Burgess, Hannah M., Shah, Sahil B., Mohr, Ian, Glaunsinger, Britt A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8903303/ https://www.ncbi.nlm.nih.gov/pubmed/35202449 http://dx.doi.org/10.1371/journal.ppat.1010099 |
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